Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine�…

Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor�…

Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative
metrics—the so-called radiomic features—within medical images. Radiomic features capture�…

The development of noninvasive methods to detect and monitor tumors continues to be a
major challenge in oncology. We used digital polymerase chain reaction–based�…

Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins�…

Abstract Background Programmed death 1 (PD-1) blockade has clinical benefit in
microsatellite-instability–high (MSI-H) or mismatch-repair–deficient (dMMR) tumors after�…

Purpose: Colorectal cancer prognosis is currently predicted from pathologic staging,
providing limited discrimination for Dukes stage B and C disease. Additional markers for�…

Background Pembrolizumab has shown improved progression-free survival versus
chemotherapy in patients with newly diagnosed microsatellite instability-high or mismatch�…

Background The role of adjuvant chemotherapy in stage II colon cancer continues to be
debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor�…

Purpose SIRFLOX was a randomized, multicenter trial designed to assess the efficacy and
safety of adding selective internal radiation therapy (SIRT) using yttrium-90 resin�…