Attention-deficit/hyperactivity disorder (ADHD) is a chronic developmental disorder affecting
3–7% of children. In light of the growing utilization of yoga, mindfulness, and meditation in�…

The spatial relation between mitochondria and endoplasmic reticulum (ER) in living HeLa
cells was analyzed at high resolution in three dimensions with two differently colored�…

Fluorescence in situ hybridization (FISH) and digital imaging microscopy were modified to
allow detection of single RNA molecules. Oligodeoxynucleotide probes were synthesized�…

Eukaryotic cilia are assembled via intraflagellar transport (IFT) in which large protein
particles are motored along ciliary microtubules. The IFT particles are composed of at least�…

Calcium is believed to control a variety of cellular processes, often with a high degree of
spatial and temporal precision. For a cell to use Ca2+ in this manner, mechanisms must�…

Within the circulatory system, blood flow regulates vascular remodelling, stimulates blood
stem cell formation, and has a role in the pathology of vascular disease. During vertebrate�…

Although the physiological relevance of mitochondrial Ca2+ homeostasis is widely
accepted, no information is yet available on the molecular identity of the proteins involved in�…

The measurement of intracellular calcium ion concentrations ([Ca 2+] i) in single living cells
using quantitative fluorescence microscopy draws from a diverse set of disciplines, including�…

Luminous proteins include primary light producers, such as aequorin, and secondary
photoproteins that in some organisms red-shift light emission for better penetration in space�…

The concentration of intracellular free calcium ([Ca2+] i) in polarized eosinophils was
imaged during chemotaxis by monitoring fluorescence of the calcium-sensitive dye Fura-2�…