Micronuclei (MN) and other nuclear anomalies such as nucleoplasmic bridges (NPBs) and
nuclear buds (NBUDs) are biomarkers of genotoxic events and chromosomal instability�…

The study of DNA damage at the chromosome level is an essential part of genetic toxicology
because chromosomal mutation is an important event in carcinogenesis. The micronucleus�…

The International Collaborative Project on Micronucleus Frequency in Human Populations
(HUMN) was organized to collect data on micronucleus (MN) frequencies in different human�…

Criteria for scoring micronuclei and nucleoplasmic bridges in binucleated cells in the
cytokinesis-block micronucleus assay for isolated human lymphocyte cultures are described�…

The micronucleus technique has been proposed as a method for measurement of
chromosomal damage in mitogen-stimulated human lymphocytes. Micronuclei require one�…

The cytokinesis-block micronucleus cytome assay is a comprehensive system for measuring
DNA damage, cytostasis and cytotoxicity. DNA damage events are scored specifically in�…

The frequency of micronuclei (MN) in peripheral blood lymphocytes (PBL) is extensively
used as a biomarker of chromosomal damage and genome stability in human populations�…

The development of the cytokinesis-block (CB) technique has transformed the human-
lymphocyte micronucleus assay (MN) into a reliable and precise method for assessing�…

The cytokinesis-block micronucleus technique was developed to overcome the kinetic
problems inherent in the use of human lymphocytes for micronucleus assays. Using this�…

The cytokinesis-block micronucleus (CBMN) assay was originally developed as an ideal
system for measuring micronuclei (MNi) however it can also be used to measure�…