[HTML][HTML] Global analysis of X-chromosome dosage compensation

V Gupta, M Parisi, D Sturgill, R Nuttall, M Doctolero…�- Journal of biology, 2006 - Springer
Background Drosophila melanogaster females have two X chromosomes and two autosome
sets (XX; AA), while males have a single X chromosome and two autosome sets (X; AA)�…

Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein+ presenilin-1 transgenic mice

CA Dickey, JF Loring, J Montgomery…�- Journal of�…, 2003 - Soc Neuroscience
A critical question in Alzheimer's disease (AD) research is the cause of memory loss that
leads to dementia. The amyloid precursor protein+ presenilin-1 (APP+ PS1) transgenic�…

An evaluation of the performance of cDNA microarrays for detecting changes in global mRNA expression

H Yue, PS Eastman, BB Wang, J Minor…�- Nucleic acids�…, 2001 - academic.oup.com
The cDNA microarray is one technological approach that has the potential to accurately
measure changes in global mRNA expression levels. We report an assessment of an�…

Qdot nanobarcodes for multiplexed gene expression analysis

PS Eastman, W Ruan, M Doctolero, R Nuttall…�- Nano Letters, 2006 - ACS Publications
We report a quantum dot (Qdot) nanobarcode-based microbead random array platform for
accurate and reproducible gene expression profiling in a high-throughput and multiplexed�…

[HTML][HTML] Characterization of a multiplex, 12-biomarker test for rheumatoid arthritis

PS Eastman, WC Manning, F Qureshi, D Haney…�- …�of pharmaceutical and�…, 2012 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that primarily involves the joints.
Accurate and frequent assessment of RA disease activity is critical to optimal treatment�…

Maternal viral genotypic zidovudine resistance and infrequent failure of zidovudine therapy to prevent perinatal transmission of human immunodeficiency virus type 1�…

PS Eastman, DE Shapiro, RW Coombs…�- The Journal of�…, 1998 - academic.oup.com
Maternal samples were assessed from 96 women enrolled in Pediatric AIDS Clinical Trials
Group protocol 076 to determine the prevalence of human immunodeficiency virus type 1�…

Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir)�…

PS Eastman, J Mittler, R Kelso, C Gee, E Boyer…�- Journal of�…, 1998 - Am Soc Microbiol
ABSTRACT Ten subjects received 600 to 1,200 mg of the human immunodeficiency virus
type 1 (HIV-1) protease inhibitor ritonavir per day. Following 2 weeks of therapy, plasma HIV�…

Correlation of serum protein biomarkers with disease activity in psoriatic arthritis

TA Boyd, PS Eastman, DH Huynh…�- Expert Review of�…, 2020 - Taylor & Francis
Objective: To assess the correlation of serum protein biomarkers with disease activity across
different domains of psoriatic arthritis (PsA). Material and methods: A cross-sectional cohort�…

[HTML][HTML] Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis

X Zhao, F Qureshi, PS Eastman, WC Manning…�- Journal of�…, 2012 - Elsevier
Variability in pre-analytical blood sampling and handling can significantly impact results
obtained in quantitative immunoassays. Understanding the impact of these variables is�…

Randomized, controlled phase I/II, trial of combination therapy with delavirdine (U-90152S) and conventional nucleosides in human immunodeficiency virus type 1�…

RT Davey Jr, DG Chaitt, GF Reed…�- Antimicrobial agents�…, 1996 - Am Soc Microbiol
Delavirdine mesylate (DLV) is a potent nonnucleoside reverse transcriptase inhibitor with
activity specific for human immunodeficiency virus type 1. In the present phase I/II study we�…