The historical co-evolution of biological motility models with models of Brownian motion is
outlined. Recent results for how to derive cell-type-specific motility models from experimental�…

We report on a microfluidic particle-separation device that makes use of the asymmetric
bifurcation of laminar flow around obstacles. A particle chooses its path deterministically on�…

The social amoebae are exceptional in their ability to alternate between unicellular and
multicellular forms. Here we describe the genome of the best-studied member of this group�…

Protein levels have been shown to vary substantially between individual cells in clonal
populations. In prokaryotes, the contribution to such fluctuations from the inherent�…

We track the motion of individual fluorescently labeled mRNA molecules inside live E. coli
cells. We find that the motion is subdiffusive, with an exponent that is robust to physiological�…

Cells use protein-DNA and protein-protein interactions to regulate transcription. A
biophysical understanding of this process has, however, been limited by the lack of methods�…

We used single-molecule imaging techniques and measured the one-dimensional diffusion
of LacI repressor proteins along elongated DNA to address the long-standing puzzle of why�…

We show that genomic-length DNA molecules imaged in nanochannels have an extension
along the channel that scales linearly with the contour length of the polymer, in agreement�…

Dielectrophoretic trapping of molecules is typically carried out using metal electrodes to
provide high field gradients. In this paper we demonstrate dielectrophoretic trapping using�…

Miniaturization to the micrometer and nanometer scale opens up the possibility to probe
biology on a length scale where fundamental biological processes take place, such as the�…