Accurate chromosome segregation in mitosis is crucial to maintain a diploid chromosome
number. A majority of cancer cells are aneuploid and chromosomally unstable, ie they tend�…

Accurate chromosome segregation depends on the proper attachment of sister kinetochores
to microtubules emanating from opposite spindle poles. Merotelic kinetochore orientation is�…

Proper chromosome segregation is required to maintain the appropriate number of
chromosomes from one cell generation to the next and to prevent aneuploidy, the condition�…

In mitotic cells, an error in chromosome segregation occurs when a chromosome is left near
the spindle equator after anaphase onset (lagging chromosome). In PtK1 cells, we found�…

Merotelic kinetochore orientation is an error that occurs when a single kinetochore becomes
attached to microtubules from two spindle poles rather than just to one pole. We obtained�…

Merotelic kinetochore orientation is a misattachment in which a single kinetochore binds
microtubules from both spindle poles rather than just one and can produce anaphase�…

Randomized, prospective trial of bilevel versus continuous p... : Critical Care Medicine
Randomized, prospective trial of bilevel versus continuous positive airway pressure in acute�…

Mitotic cells face the challenging tasks of linking kinetochores to growing and shortening
microtubules and actively regulating these dynamic attachments to produce accurate�…

Background: The spindle assembly checkpoint (SAC) imparts fidelity to chromosome
segregation by delaying anaphase until all sister chromatid pairs have become bipolarly�…

Merotelic kinetochore orientation is a kinetochore misattachment in which a single
kinetochore is attached to microtubules from both spindle poles instead of just one. It can be�…