SR proteins and splicing control 1569
DEVELOFMEIST Page 1 VOLUME 10 GENES (Eh DEVELOFMEIST NUMBER 13 PAGES
1569-1710 July 1, 1996 EDITORIAL BOARD J. Adams (Melbourne, Australia) J. Beckwith (Boston�…
1569-1710 July 1, 1996 EDITORIAL BOARD J. Adams (Melbourne, Australia) J. Beckwith (Boston�…
Segmental trisomy as a mouse model for Down syndrome.
MT Davisson, C Schmidt, RH Reeves…�- Progress in clinical�…, 1993 - europepmc.org
Mice trisomic for Chromosome (Chr) 16 have been used extensively as an animal model for
human Down Syndrome (Trisomy 21). This system has drawbacks, however: trisomy for all�…
human Down Syndrome (Trisomy 21). This system has drawbacks, however: trisomy for all�…
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium
AY Nikitin, A Alcaraz, MR Anver, RT Bronson…�- Cancer research, 2004 - AACR
Rapid advances in generating new mouse genetic models for lung neoplasia provide a
continuous challenge for pathologists and investigators. Frequently, phenotypes of new�…
continuous challenge for pathologists and investigators. Frequently, phenotypes of new�…
[HTML][HTML] Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
T Komori, H Yagi, S Nomura, A Yamaguchi, K Sasaki…�- cell, 1997 - cell.com
A transcription factor, Cbfa1, which belongs to the runt-domain gene family, is expressed
restrictively in fetal development. To elucidate the function of Cbfa1, we generated mice with�…
restrictively in fetal development. To elucidate the function of Cbfa1, we generated mice with�…
[HTML][HTML] Identification of bronchioalveolar stem cells in normal lung and lung cancer
CFB Kim, EL Jackson, AE Woolfenden, S Lawrence…�- Cell, 2005 - cell.com
Injury models have suggested that the lung contains anatomically and functionally distinct
epithelial stem cell populations. We have isolated such a regional pulmonary stem cell�…
epithelial stem cell populations. We have isolated such a regional pulmonary stem cell�…
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
A Yang, R Schweitzer, D Sun, M Kaghad, N Walker…�- Nature, 1999 - nature.com
The p63 gene, a homologue of the tumour-suppressor p53 (–), is highly expressed in the
basal or progenitor layers of many epithelial tissues. Here we report that mice homozygous�…
basal or progenitor layers of many epithelial tissues. Here we report that mice homozygous�…
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
AA Beg, WC Sha, RT Bronson, S Ghosh, D Baltimore�- Nature, 1995 - nature.com
NF-κB, which consists of two polypeptides, p50 (Mr 50K) and p65/RelA (Mr 65K), is thought
to be a key regulator of genes involved in responses to infection, inflammation and stress1�…
to be a key regulator of genes involved in responses to infection, inflammation and stress1�…
Tumor spectrum analysis in p53-mutant mice
T Jacks, L Remington, BO Williams, EM Schmitt…�- Current biology, 1994 - cell.com
Background: The p53 tumor suppressor gene is mutated in a large percentage of human
malignancies, including tumors of the colon, breast, lung and brain. Individuals who inherit�…
malignancies, including tumors of the colon, breast, lung and brain. Individuals who inherit�…
Effects of an Rb mutation in the mouse
T Jacks, A Fazeli, EM Schmitt, RT Bronson, MA Goodell…�- Nature, 1992 - nature.com
The retinoblastoma gene is mutated in several types of human cancer and is the best
characterized of the tumour-suppressor genes. A mouse strain has been constructed in�…
characterized of the tumour-suppressor genes. A mouse strain has been constructed in�…
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson, N Willis, K Mercer, RT Bronson…�- Genes &�…, 2001 - genesdev.cshlp.org
Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin
and the stages of progression of this tumor type are not well understood. We have�…
and the stages of progression of this tumor type are not well understood. We have�…