Accurate forecasting of energy consumption in a building is an important strategy in
achieving the goal of reducing energy demand, as well as to improve energy efficiency. To�…

A long-standing hypothesis on tumorigenesis is that cell division failure, generating
genetically unstable tetraploid cells, facilitates the development of aneuploid malignancies�…

Metabolic reprograming is an emerging hallmark of tumor biology and an actively pursued
opportunity in discovery of oncology drugs. Extensive efforts have focused on therapeutic�…

Aurora-A is a mitotic kinase that regulates mitotic spindle formation and segregation. In
multiple myeloma (MM), high Aurora-A gene expression has been correlated with�…

Multiple myeloma (MM) remains incurable despite novel therapies, suggesting the need for
further identification of factors mediating tumorigenesis and drug resistance. Using both in�…

Membrane processes are increasingly being considered as an alternative to conventional
water and waste water treatment methods in anticipation of future demands for high�…

Bortezomib therapy has proven successful for the treatment of relapsed, relapsed/refractory,
and newly diagnosed multiple myeloma (MM). At present, bortezomib is available as an�…

The bone marrow (BM) microenvironment consists of extracellular-matrix and the cellular
compartment including immune cells. Multiple myeloma (MM) cell and BM accessory cell�…

The stiff human foot enables an efficient push-off when walking or running, and was critical
for the evolution of bipedalism,,,,–. The uniquely arched morphology of the human midfoot is�…

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