In this issue of Brain, Brunklaus et al. report a study of 241 patients with Dravet syndrome
carrying a SCN1A mutation, with the aim of identifying predictors of developmental outcome�…

Dravet syndrome is a severe epilepsy syndrome of infancy characterised by seizures of
multiple types, often prolonged and particularly fever-sensitive, with onset in the first year of�…

BACKGROUND: SCN1A is the most clinically relevant epilepsy gene, most mutations
causing Dravet syndrome (also known as severe myoclonic epilepsy of infancy or SMEI). We�…

Dravet syndrome is a rare and severe type of epilepsy.“Severe myoclonic epilepsy in
infancy” was first described in 1978 by Charlotte Dravet, who observed common features�…

Severe myoclonic epilepsy of infancy (SMEI) is a complex form of epilepsy that was first
described in France in 1978. Because the myoclonic component of this epilepsy is not�…

Severe myoclonic epilepsy in infancy (SMEI) is a genetically determined severe epileptic
encephalopathy that was first described by Charlotte Dravet in 19781 and was included in�…

Dravet syndrome is an epilepsy syndrome of infantile onset, frequently caused by SCN1A
mutations or deletions. Its prevalence, long-term evolution in adults and neuropathology are�…

We present two children who exhibited the characteristics of Dravet syndrome during infancy
and young childhood, with SCN1A mutation, but nevertheless achieved seizure freedom for�…

Richard P. Morse, MD Dravet syndrome is a severe childhood epilepsy characterized by
intractable seizures and neurodevelopmental delay. First described in 1978 by Dravet as�…

Dravet syndrome (DS) is a severe form of infantile onset epilepsy characterized by multiple
seizure types, prolonged convulsive seizures and frequent episodes of status epilepticus�…