The developing brain is especially sensitive to a wide range of experiences, showing a
remarkable capacity for plastic changes that influence behavioural outcomes throughout the�…

Objective: To review general principles of brain development, identify basic principles of
brain plasticity, and discuss factors that influence brain development and plasticity. Method�…

The developing normal brain shows a remarkable capacity for plastic change in response to
a wide range of experiences including sensory and motor experience, psychoactive drugs�…

Background Neuroplasticity refers to the inherently dynamic biological capacity of the central
nervous system (CNS) to undergo maturation, change structurally and functionally in�…

Clinical disorders of brain plasticity are common in the practice of child neurology. Children
have an enhanced capacity for brain plasticity compared to adults as demonstrated by their�…

Although the brain was once seen as a rather static organ, it is now clear that the
organization of brain circuitry is constantly changing as a function of experience. These�…

We conceptualize brain plasticity as an intrinsic property of the nervous system enabling
rapid adaptation in response to changes in an organism's internal and external environment�…

Epigenetics is changing the interpretation of “genetics” in relation to “environment”, in that
the genetic code is not exclusively responsible for the “destiny” of a child's development;�…

Although the potential vulnerability of children's brain development is generally recognized,
relatively little is known about the timing, resiliency, or mechanisms involved. While animal�…

The developing brain experiences major construction during fetal life and for at least the first
decade of childhood. Many more neurons and synaptic connections are produced than are�…