Deep brain stimulation is an effective treatment for Parkinson's disease but can be
complicated by side-effects such as cognitive decline. There is often a delay before this side�…

Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may
depend on connectivity between the stimulation site and other brain regions, but which�…

The subthalamic nucleus and internal pallidum are main target sites for deep brain
stimulation in Parkinson's disease. Multiple trials that investigated subthalamic versus�…

Subthalamic nucleus deep brain stimulation is an effective treatment for advanced
Parkinson's disease; however, its therapeutic mechanism is unclear. Previous modelling of�…

This study aimed to identify functional neuroimaging patterns anticipating the clinical
indication for deep brain stimulation (DBS) in patients with Parkinson's disease (PD). A�…

Deep brain stimulation therapy is an effective symptomatic treatment for Parkinson's
disease, yet the precise mechanisms responsible for its therapeutic effects remain unclear�…

Objective This study was undertaken to describe relationships between electrode
localization and motor outcomes from the subthalamic nucleus (STN) deep brain stimulation�…

Background Positive clinical outcomes are now well established for deep brain stimulation,
but little is known about the effects of long-term deep brain stimulation on brain structural�…

Neuroimaging has seen a paradigm shift away from a formal description of local activity
patterns towards studying distributed brain networks. The recently defined framework of the�…

Deep brain stimulation of the subthalamic nucleus has become a standard therapy for
Parkinson's disease. Despite extensive experience, however, the precise target of optimal�…