Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared�…

Neuropsychiatric disorders are increasingly conceptualized as overlapping spectra sharing
multi-level neurobiological alterations. However, whether transdiagnostic cortical alterations�…

Psychiatric disorders are phenotypically heterogeneous entities with a complex genetic
basis. To mitigate this complexity, many investigators study so-called intermediate�…

Macroscale white matter pathways are the infrastructure for large-scale communication in
the human brain and a prerequisite for healthy brain function. Disruptions in the brain's�…

It is increasingly recognized that multiple psychiatric conditions are underpinned by shared
neural pathways, affecting similar brain systems. Here, we carried out a multiscale neural�…

Rapid advances in neuroimaging and network science have produced powerful tools and
measures to appreciate human brain organization at multiple spatial and temporal scales. It�…

Many human brain disorders are associated with characteristic alterations in the structural
and functional connectivity of the brain. In this article, we explore how commonalities and�…

The panoply of cognitive, affective, motivational, and social functions that underpin everyday
human experience requires precisely choreographed patterns of interaction between�…

At macroscopic scales, the human connectome comprises anatomically distinct brain areas,
the structural pathways connecting them and their functional interactions. Annotation of�…

Gene networks have yielded numerous neurobiological insights, yet an integrated view
across brain regions is lacking. We leverage RNA sequencing in 864 samples representing�…