Background Irritable bowel syndrome‐diarrhoea (IBS‐D) and IBS‐mixed stool pattern (IBS‐
M) are disorders of gut‐brain interaction characterised by abdominal pain associated with�…

Irritable bowel syndrome (IBS) is one of the most common disorders of the gut-brain axis,
which affects approximately 4% of the global population. The Rome IV criteria define IBS as�…

IBS is a functional gastrointestinal disorder which has been subtyped according to bowel
habits. This review presents recommendations for IBS-D which makes up about 1/3 of all�…

Objective Over half of patients with IBS have either diarrhoea (IBS-D) or a mixed stool
pattern (IBS-M). The relative efficacy of licenced pharmacological therapies is unclear in the�…

Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) condition involving
numerous potential causative factors (eg alterations in gut microbiota, motility, brain–gut�…

Key studies published in 2022 further established the importance of alterations in the gut
microenvironment and interactions with the enteric and central nervous systems in symptom�…

Background Irritable bowel syndrome (IBS) is multifactorial in nature, and a wide range of
therapies is available to manage symptoms of this common disorder. Aim To provide an�…

The irritable bowel syndrome (IBS) is part of the spectrum of functional bowel disorders
characterised by a diverse consortium of abdominal symptoms including abdominal pain�…

Irritable bowel syndrome (IBS) causes gastrointestinal symptoms such as abdominal pain,
bloating, and bowel pattern abnormalities, which compromise patients' daily functioning�…

The objectives of this narrative review are to update readers on the current state-of-the-art
regarding diverse approaches for the treatment of pain, global symptoms, or adequate relief�…