Therapeutic cancer vaccines

M Saxena, SH van der Burg, CJM Melief…�- Nature Reviews�…, 2021 - nature.com
Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better
understanding of the breadth of tumour-associated antigens, the native immune response�…

[HTML][HTML] Cancer vaccines: the next immunotherapy frontier

MJ Lin, J Svensson-Arvelund, GS Lubitz, A Marabelle…�- Nature cancer, 2022 - nature.com
After several decades, therapeutic cancer vaccines now show signs of efficacy and potential
to help patients resistant to other standard-of-care immunotherapies, but they have yet to�…

Therapeutic cancer vaccines: past, present, and future

C Guo, MH Manjili, JR Subjeck, D Sarkar…�- Advances in cancer�…, 2013 - Elsevier
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results�…

[HTML][HTML] Combining cancer vaccines with immunotherapy: establishing a new immunological approach

CG Kim, YB Sang, JH Lee, HJ Chon�- International Journal of Molecular�…, 2021 - mdpi.com
Therapeutic cancer vaccines have become increasingly qualified for use in personalized
cancer immunotherapy. A deeper understanding of tumor immunology and novel antigen�…

[HTML][HTML] Cancer vaccines: Promising therapeutics or an unattainable dream

H Donninger, C Li, JW Eaton, K Yaddanapudi�- Vaccines, 2021 - mdpi.com
The advent of cancer immunotherapy has revolutionized the field of cancer treatment and
offers cancer patients new hope. Although this therapy has proved highly successful for�…

[HTML][HTML] Therapeutic cancer vaccines: advancements, challenges, and prospects

T Fan, M Zhang, J Yang, Z Zhu, W Cao…�- Signal Transduction and�…, 2023 - nature.com
With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the�…

Cancer vaccines in the clinic

ME Janes, AP Gottlieb, KS Park, Z Zhao…�- Bioengineering &�…, 2024 - Wiley Online Library
Vaccines are an important tool in the rapidly evolving repertoire of immunotherapies in
oncology. Although cancer vaccines have been investigated for over 30 years, very few�…

[HTML][HTML] Turning the corner on therapeutic cancer vaccines

RE Hollingsworth, K Jansen�- npj Vaccines, 2019 - nature.com
Recent advances in several areas are rekindling interest and enabling progress in the
development of therapeutic cancer vaccines. These advances have been made in target�…

[PDF][PDF] Enhancing immune responses to tumor-associated antigens

JP Higgins, MB Bernstein, JW Hodge�- Cancer biology & therapy, 2009 - Taylor & Francis
The goal of vaccine-based cancer immunotherapy is to induce a tumor-specific immune
response that ultimately reduces tumor burden. However, the immune system is often�…

Cancer vaccines: toward the next breakthrough in cancer immunotherapy

Y Igarashi, T Sasada�- Journal of immunology research, 2020 - Wiley Online Library
Until now, three types of well‐recognized cancer treatments have been developed, ie,
surgery, chemotherapy, and radiotherapy; these either remove or directly attack the cancer�…