The multifaceted role of the ventromedial prefrontal cortex in emotion, decision making, social cognition, and psychopathology

J Hiser, M Koenigs�- Biological psychiatry, 2018 - Elsevier
The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this�…

Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders

B Myers-Schulz, M Koenigs�- Molecular psychiatry, 2012 - nature.com
In recent years, an increasing number of neuroimaging studies have sought to identify the
brain anomalies associated with mood and anxiety disorders. The results of such studies�…

Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans

JC Motzkin, CL Philippi, RC Wolf, MK Baskaya…�- Biological�…, 2015 - Elsevier
Background Dysfunction in the ventromedial prefrontal cortex (vmPFC) is believed to play a
pivotal role in the pathogenesis of mood and anxiety disorders. Leading neurocircuitry�…

Why we need nonhuman primates to study the role of ventromedial prefrontal cortex in the regulation of threat-and reward-elicited responses

AC Roberts, HF Clarke�- Proceedings of the National�…, 2019 - National Acad Sciences
The ventromedial prefrontal cortex (vmPFC) is consistently implicated in the cognitive and
emotional symptoms of many psychiatric disorders, but the causal mechanisms of its�…

Ventromedial prefrontal cortex damage is associated with decreased ventral striatum volume and response to reward

MS Pujara, CL Philippi, JC Motzkin…�- Journal of�…, 2016 - Soc Neuroscience
The ventral striatum and ventromedial prefrontal cortex (vmPFC) are two central nodes of the
“reward circuit” of the brain. Human neuroimaging studies have demonstrated coincident�…

Human lesion studies of ventromedial prefrontal cortex

B Schneider, M Koenigs�- Neuropsychologia, 2017 - Elsevier
Studies of neurological patients with focal lesions involving ventromedial prefrontal cortex
(vmPFC) have demonstrated a critical role for this brain area in various aspects of cognition�…

Ventromedial prefrontal-subcortical systems and the generation of affective meaning

M Roy, D Shohamy, TD Wager�- Trends in cognitive sciences, 2012 - cell.com
The ventromedial prefrontal cortex (vmPFC) comprises a set of interconnected regions that
integrate information from affective sensory and social cues, long-term memory, and�…

[HTML][HTML] The contribution of distinct subregions of the ventromedial frontal cortex to emotion, social behavior, and decision making

PH Rudebeck, DM Bannerman…�- Cognitive, Affective, &�…, 2008 - Springer
Damage to the ventromedial frontal cortex (VMFC) in humans is associated with deficits in
decision making. Decision making, however, often happens while people are interacting�…

Ventromedial prefrontal cortex and the regulation of physiological arousal

S Zhang, S Hu, HH Chao, JS Ide, X Luo…�- Social cognitive and�…, 2014 - academic.oup.com
Neuroimaging studies show a correlation between activity of the ventromedial prefrontal
cortex (vmPFC) and skin conductance measurements. However, little is known whether this�…

Damage to the left ventromedial prefrontal cortex impacts affective theory of mind

A Leopold, F Krueger, O Dal Monte…�- Social Cognitive and�…, 2012 - academic.oup.com
Studies investigating theory of mind (ToM) abilities (ie ability to understand and predict
others' mental states) have revealed that affective and cognitive functions play a significant�…