Kidney tubular cell death induced by transforming growth factor-β1 (TGF-β1) is known to
contribute to diabetic nephropathy, a major complication of diabetes. Caspase-3-dependent�…

Ferroptosis is a novel type of programmed cell death characterized by iron-dependent
accumulation of lipid hydroperoxides to lethal levels. Accumulative studies have indicated�…

Background Ferroptosis is a recently identified iron-dependent form of cell death as a result
of increased reactive oxygen species (ROS) and lipid peroxidation. In this study, we�…

Background: Ferroptosis, an iron-dependent form of regulated necrosis mediated by lipid
peroxidation, predominantly polyunsaturated fatty acids, is involved in postischemic and�…

Cell death is a finely regulated process occurring through different pathways. Regulated cell
death, either through apoptosis or regulated necrosis offers the possibility of therapeutic�…

Ferroptosis, a novel form of regulated cell death, is characterized by imbalance of
intracellular iron and redox systems, resulting from overgeneration of toxic lipid peroxidation�…

Ferroptosis is a newly identified form of regulated cell death driven by iron-dependent
phospholipid peroxidation and oxidative stress. Ferroptosis has distinct biological and�…

Ferroptosis is a recently recognized form of nonapoptotic cell death that is triggered by
reactive oxidative species (ROS) due to iron overload, lipid peroxidation accumulation, or�…

Ferroptosis is a non-traditional form of regulated cell death, characterized by iron overload
and lipid peroxidation. Exploration of ferroptosis in chronic kidney disease (CKD) has been�…

BACKGROUND Endothelial dysfunction, a hallmark of diabetes, is a critical and initiating
contributor to the pathogenesis of diabetic cardiovascular complications. However, the�…