An investigation of the single and combined phthalate metabolite effects on human chorionic gonadotropin expression in placental cells

JJ Adibi, Y Zhao, LV Zhan, M Kapidzic…�- Environmental�…, 2017 - ehp.niehs.nih.gov
Background: Observational studies have reported associations between maternal phthalate
levels and adverse outcomes at birth and in the health of the child. Effects on placental�…

Phthalate exposures and placental health in animal models and humans: a systematic review

TN Seymore, Z Rivera-Nunez, PA Stapleton…�- Toxicological�…, 2022 - academic.oup.com
Phthalates are ubiquitous compounds known to leach from the plastic products that contain
them. Due to their endocrine-disrupting properties, a wide range of studies have elucidated�…

Transcriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposure

JJ Adibi, RM Whyatt, R Hauser, HK Bhat…�- Environmental�…, 2010 - ehp.niehs.nih.gov
Background Phthalates can alter steroidogenesis and peroxisome proliferator–activated
receptor gamma (PPARγ)–mediated transcription in rodent tissues. The placenta offers a�…

Monitoring phthalates in maternal and cord blood: implications for prenatal exposure and birth outcomes

HL Hwa, FS Peng, TT Ting, HW Chen…�- Environmental�…, 2022 - Wiley Online Library
Although many phthalates are endocrine‐disrupting chemicals that are associated with
adverse birth outcomes, the relationship between maternal phthalate exposure and birth�…

Association between pregnancy loss and urinary phthalate levels around the time of conception

G Toft, BAG J�nsson, CH Lindh…�- Environmental�…, 2012 - ehp.niehs.nih.gov
Background: Animal studies indicate that some phthalate metabolites may harm female
reproductive function. Objectives: We assessed the associations between exposure to�…

Association between prenatal exposure to phthalates and the health of newborns

PC Huang, PL Kuo, YY Chou, SJ Lin, CC Lee�- Environment International, 2009 - Elsevier
Phthalates are developmental and reproductive toxicants for the fetus in pregnant rodents,
and the ability of phthalates to penetrate the placenta have been reported. The aims of this�…

Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age

KM Main, GK Mortensen, MM Kaleva…�- Environmental�…, 2006 - ehp.niehs.nih.gov
Phthalates adversely affect the male reproductive system in animals. We investigated
whether phthalate monoester contamination of human breast milk had any influence on the�…

[HTML][HTML] Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study

S Santos, CM Sol, C van Zwol–Janssens…�- Environment�…, 2021 - Elsevier
Importance Exposure to phthalates may affect fetal growth, but previous studies are
inconsistent and have not explored the trimester-specific effects of phthalates on repeated�…

Phthalate exposure among pregnant women in Jerusalem, Israel: results of a pilot study

T Berman, D Hochner-Celnikier, AM Calafat…�- Environment�…, 2009 - Elsevier
BACKGROUND: Phthalates can disrupt endocrine function and induce reproductive and
developmental toxicity in laboratory animals. Few studies have evaluated exposure to�…

Associations between maternal phthalate exposure and cord sex hormones in human infants

LC Lin, SL Wang, YC Chang, PC Huang, JT Cheng…�- Chemosphere, 2011 - Elsevier
It has been speculated that maternal phthalate exposure may affect reproductive
development in human newborns. However, the mechanism awaits further investigation�…