[HTML][HTML] Molecular signatures and cellular diversity during mouse habenula development
LL van de Haar, D Riga, JE Boer, O Garritsen, Y Adolfs…�- Cell reports, 2022 - cell.com
The habenula plays a key role in various motivated and pathological behaviors and is
composed of molecularly distinct neuron subtypes. Despite progress in identifying mature�…
composed of molecularly distinct neuron subtypes. Despite progress in identifying mature�…
[HTML][HTML] Transcriptional and spatial resolution of cell types in the mammalian habenula
The habenula complex is appreciated as a critical regulator of motivated and pathological
behavioral states via its output to midbrain nuclei. Despite this, transcriptional definition of�…
behavioral states via its output to midbrain nuclei. Despite this, transcriptional definition of�…
Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis
S Fore, F Acu�a-Hinrichsen, KA Mutlu…�- Science�…, 2020 - science.org
The developing brain undergoes drastic alterations. Here, we investigated developmental
changes in the habenula, a brain region that mediates behavioral flexibility during learning�…
changes in the habenula, a brain region that mediates behavioral flexibility during learning�…
[HTML][HTML] Anatomical and single-cell transcriptional profiling of the murine habenular complex
The lateral habenula (LHb) is an epithalamic brain structure critical for processing and
adapting to negative action outcomes. However, despite the importance of LHb to behavior�…
adapting to negative action outcomes. However, despite the importance of LHb to behavior�…
[HTML][HTML] Zebrafish tools for deciphering habenular network-linked mental disorders
A B�hler, M Carl�- Biomolecules, 2021 - mdpi.com
Simple Summary Everything that we think, feel or do depends on the function of neural
networks in the brain. These are highly complex structures made of cells (neurons) and their�…
networks in the brain. These are highly complex structures made of cells (neurons) and their�…
The molecular mechanisms controlling morphogenesis and wiring of the habenula
ERE Schmidt, RJ Pasterkamp�- Pharmacology Biochemistry and Behavior, 2017 - Elsevier
The habenula is an evolutionarily conserved brain region comprising bilaterally paired
nuclei that plays a key role in processing reward information and mediating aversive�…
nuclei that plays a key role in processing reward information and mediating aversive�…
[HTML][HTML] Phylogeny and ontogeny of the habenular structure
Habenula is an epithalamic nucleus connecting the forebrain with the ventral midbrain and
hindbrain that plays a pivotal role in decision making by regulating dopaminergic and�…
hindbrain that plays a pivotal role in decision making by regulating dopaminergic and�…
[HTML][HTML] Transcriptomic characterization of the human habenula highlights drug metabolism and the neuroimmune system
Due to size and accessibility, most information about the habenula is derived from rodent
studies. To better understand the molecular signature of the habenula we characterized the�…
studies. To better understand the molecular signature of the habenula we characterized the�…
Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development
LA Quina, S Wang, L Ng, EE Turner�- Journal of Neuroscience, 2009 - Soc Neuroscience
The habenula is a dorsal diencephalic structure consisting of medial and lateral subnuclei
and a principal output tract, the fasciculus retroflexus, which together form a link between the�…
and a principal output tract, the fasciculus retroflexus, which together form a link between the�…
[HTML][HTML] Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons
YA Lee, Y Goto�- PloS one, 2011 - journals.plos.org
Background The habenula plays an important role on cognitive and affective functions by
regulating monoamines transmission such as the dopamine and serotonin, such that its�…
regulating monoamines transmission such as the dopamine and serotonin, such that its�…