Non-Smad signaling pathways of the TGF-β family
YE Zhang�- Cold Spring Harbor perspectives in biology, 2017 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) and structurally related factors use several intracellular
signaling pathways in addition to Smad signaling to regulate a wide array of cellular�…
signaling pathways in addition to Smad signaling to regulate a wide array of cellular�…
[HTML][HTML] Non-Smad pathways in TGF-β signaling
YE Zhang�- Cell research, 2009 - nature.com
Transforming growth factor-β utilizes a multitude of intracellular signaling pathways in
addition to Smads to regulate a wide array of cellular functions. These non-canonical, non�…
addition to Smads to regulate a wide array of cellular functions. These non-canonical, non�…
New insights into TGF-β–Smad signalling
P ten Dijke, CS Hill�- Trends in biochemical sciences, 2004 - cell.com
Transforming growth factor β (TGF-β) initiates its diverse cellular responses by binding to
and activating specific cell surface receptors that have intrinsic serine/threonine kinase�…
and activating specific cell surface receptors that have intrinsic serine/threonine kinase�…
Transforming growth factor-β receptors and Smads: regulatory complexity and functional versatility
EH Budi, D Duan, R Derynck�- Trends in cell biology, 2017 - cell.com
Transforming growth factor (TGF)-β family proteins control cell physiology, proliferation, and
growth, and direct cell differentiation, thus playing key roles in normal development and�…
growth, and direct cell differentiation, thus playing key roles in normal development and�…
Non-Smad TGF-β signals
A Moustakas, CH Heldin�- Journal of cell science, 2005 - journals.biologists.com
During the past 10 years, it has been firmly established that Smad pathways are central
mediators of signals from the receptors for transforming growth factor β (TGF-β) superfamily�…
mediators of signals from the receptors for transforming growth factor β (TGF-β) superfamily�…
Posttranslational regulation of Smads
Transforming growth factor β (TGF-β) family signaling dictates highly complex programs of
gene expression responses, which are extensively regulated at multiple levels and vary�…
gene expression responses, which are extensively regulated at multiple levels and vary�…
Negative regulation of TGF-β receptor/Smad signal transduction
S Itoh, P ten Dijke�- Current opinion in cell biology, 2007 - Elsevier
Members of the transforming growth factor-β (TGF-β) family are highly conserved
multifunctional cell–cell signaling proteins that are of key importance for controlling�…
multifunctional cell–cell signaling proteins that are of key importance for controlling�…
Specificity, versatility, and control of TGF-β family signaling
R Derynck, EH Budi�- Science signaling, 2019 - science.org
Encoded in mammalian cells by 33 genes, the transforming growth factor–β (TGF-β) family
of secreted, homodimeric and heterodimeric proteins controls the differentiation of most, if�…
of secreted, homodimeric and heterodimeric proteins controls the differentiation of most, if�…
TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
B Schmierer, CS Hill�- Nature reviews Molecular cell biology, 2007 - nature.com
Ligands of the transforming growth factor-β (TGFβ) superfamily of growth factors initiate
signal transduction through a bewildering complexity of ligand–receptor interactions�…
signal transduction through a bewildering complexity of ligand–receptor interactions�…
Specificity, diversity, and regulation in TGF‐β superfamily signaling
E Piek, CH HELDIN, PTEN DIJKE�- The FASEB Journal, 1999 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) superfamily members are multifunctional cell‐cell
signaling proteins that play pivotal roles in tissue homeostasis and development of�…
signaling proteins that play pivotal roles in tissue homeostasis and development of�…