Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management�…

Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and�…

Preeclampsia, one of the most enigmatic complications of pregnancy, is considered a
pregnancy-specific disorder caused by the placenta and cured only by delivery. This article�…

For more than 65 years, Williams Textbook of Endocrinology has been the gold standard in
the field, delivering authoritative guidance on every aspect of adult and pediatric endocrine�…

Pregnancy is a dynamic process associated with significant physiological changes in the
cardiovascular system. These changes are mechanisms that the body has adapted to meet�…

Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact�…

Discusses the pathological and physiological changes inherent in the pre-eclampsia
syndrome, a disease of pregnancy, to determine its causes. Maternal deaths attributable to�…

Although intrinsic mechanisms that regulate arterial blood pressure (BP) are similar in men
and women, marked variations exist at the molecular, cellular and tissue levels. These�…

Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of�…

The etiology of preeclampsia is unknown. At present, 4 hypotheses are the subject of
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast�…