Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain�…

The ketogenic diet (KD) is a broadly effective treatment for medically refractory epilepsy.
Despite nearly a century of use, the mechanisms underlying its clinical efficacy remain�…

Background The ketogenic diet has been widely and successfully used to treat children with
drug-resistant epilepsy since the 1920s. The aim of this study was to test the efficacy of the�…

The ketogenic diet (KD) is an established, effective nonpharmacologic treatment for
intractable childhood epilepsy. The KD is provided differently throughout the world, with�…

Disease-causing variants in STXBP1 are among the most common genetic causes of
neurodevelopmental disorders. However, the phenotypic spectrum in STXBP1-related�…

The ketogenic diet, a high fat, adequate protein, low carbohydrate diet, has, during the past
decade, had a resurgence of interest for the treatment of difficult-to-control seizures in�…

Epilepsy in the pediatric and adolescent populations is a devastating condition where
individuals are prone to recurrent epileptic seizures or changes in behavior or movement�…

The ketogenic diet (KD), containing high levels of fat and low levels of carbohydrates, has
been used to treat refractory epilepsy since the 1920s. In the past few decades, there has�…

Importance It is currently unknown how often and in which ways a genetic diagnosis given to
a patient with epilepsy is associated with clinical management and outcomes. Objective To�…

More than half of patients with newly diagnosed epilepsy achieve complete seizure control
without major side-effects. Patients who continue to have seizures after initial medical�…