The discovery of the size and complexity of the human microbiome has resulted in an
ongoing reevaluation of many concepts of health and disease, including diseases affecting�…

Increasingly, researchers are discovering associations between microbiome and a wide
range of human diseases such as obesity, inflammatory bowel diseases, HIV, and so on�…

We found that the cancerous pancreas harbors a markedly more abundant microbiome
compared with normal pancreas in both mice and humans, and select bacteria are�…

Bacterial dysbiosis accompanies carcinogenesis in malignancies such as colon and liver
cancer, and has recently been implicated in the pathogenesis of pancreatic ductal�…

Current practice in the normalization of microbiome count data is inefficient in the statistical
sense. For apparently historical reasons, the common approach is either to use simple�…

There is emerging evidence that the commensal microbiota has a role in the pathogenesis
of multiple sclerosis (MS), a putative autoimmune disease of the CNS. Here, we compared�…

Objective A decade of microbiome studies has linked IBD to an alteration in the gut microbial
community of genetically predisposed subjects. However, existing profiles of gut microbiome�…

Multi-omic insights into microbiome function and composition typically advance one study at
a time. However, in order for relationships across studies to be fully understood, data must�…

The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the�…

Amplicon sequencing has revolutionized our ability to study DNA collected from
environmental samples by providing a rapid and sensitive technique for microbial�…