Combination therapy, a treatment modality that combines two or more therapeutic agents, is
a cornerstone of cancer therapy. The amalgamation of anti-cancer drugs enhances efficacy�…

Apoptosis is a form of programmed cell death that results in the orderly and efficient removal
of damaged cells, such as those resulting from DNA damage or during development�…

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and
pathological conditions. It is also one of the most studied topics among cell biologists. An�…

Cell suicide pathways, termed regulated cell death (RCD), play a critical role in organismal
development, homeostasis, and pathogenesis. Here, we provide an overview of key RCD�…

Using microarray-based profiling of isogenic prostate cancer xenograft models, we found
that a modest increase in androgen receptor mRNA was the only change consistently�…

The normal development and maintenance of the prostate is dependent on androgen acting
through the androgen receptor (AR). AR remains important in the development and�…

Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological�…

Cancer along with cardiovascular disease are the main causes of death in the industrialised
countries around the World. Conventional cancer treatments are losing their therapeutic�…

Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world�…

Prostate cancer afflicts one man in nine over the age of 65 and represents the most
frequently diagnosed cancer in American men (Coffey 1993). Early detection through serum�…