Light sheet fluorescence microscopy

EHK Stelzer, F Strobl, BJ Chang, F Preusser…�- Nature Reviews�…, 2021 - nature.com
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical�…

[HTML][HTML] Deep learning with radiomics for disease diagnosis and treatment: challenges and potential

X Zhang, Y Zhang, G Zhang, X Qiu, W Tan, X Yin…�- Frontiers in�…, 2022 - frontiersin.org
The high-throughput extraction of quantitative imaging features from medical images for the
purpose of radiomic analysis, ie, radiomics in a broad sense, is a rapidly developing and�…

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

L Cantuti-Castelvetri, R Ojha, LD Pedro, M Djannatian…�- Science, 2020 - science.org
The causative agent of coronavirus disease 2019 (COVID-19) is the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). For many viruses, tissue tropism is determined by�…

[HTML][HTML] CellProfiler 3.0: Next-generation image processing for biology

C McQuin, A Goodman, V Chernyshev…�- PLoS�…, 2018 - journals.plos.org
CellProfiler has enabled the scientific research community to create flexible, modular image
analysis pipelines since its release in 2005. Here, we describe CellProfiler 3.0, a new�…

Introducing high-valence elements into cobalt-free layered cathodes for practical lithium-ion batteries

GT Park, B Namkoong, SB Kim, J Liu, CS Yoon…�- Nature Energy, 2022 - nature.com
The elimination of Co from Ni-rich layered cathodes is considered a priority to reduce their
material cost and for sustainable development of Li-ion batteries (LIBs) as Co is becoming�…

[HTML][HTML] Democratising deep learning for microscopy with ZeroCostDL4Mic

L von Chamier, RF Laine, J Jukkala, C Spahn…�- Nature�…, 2021 - nature.com
Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and�…

Electrical and synaptic integration of glioma into neural circuits

HS Venkatesh, W Morishita, AC Geraghty, D Silverbush…�- Nature, 2019 - nature.com
High-grade gliomas are lethal brain cancers whose progression is robustly regulated by
neuronal activity. Activity-regulated release of growth factors promotes glioma growth, but�…

[HTML][HTML] Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

ML Choi, A Chappard, BP Singh, C Maclachlan…�- Nature�…, 2022 - nature.com
Aggregation of alpha-synuclein (α-Syn) drives Parkinson's disease (PD), although the initial
stages of self-assembly and structural conversion have not been directly observed inside�…

[HTML][HTML] CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity

� Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz…�- Immunity, 2020 - cell.com
Neutrophils are expanded and abundant in cancer-bearing hosts. Under the influence of
CXCR1 and CXCR2 chemokine receptor agonists and other chemotactic factors produced�…

[HTML][HTML] Genome-wide RNA polymerase stalling shapes the transcriptome during aging

A Gyenis, J Chang, JJPG Demmers, ST Bruens…�- Nature�…, 2023 - nature.com
Gene expression profiling has identified numerous processes altered in aging, but how
these changes arise is largely unknown. Here we combined nascent RNA sequencing and�…