Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging�…

Highlights•Substance use disorders (SUD) involve blunted positive affective and
physiological responses to natural rewards.•Savoring hedonic pleasure from natural�…

BACKGROUND: Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal
syndrome that can occur after intrauterine opioid exposure. Adverse neurobehavioral�…

The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal�…

Background The impact of prenatal opioid exposure on brain development remains poorly
understood. Methods We conducted a prospective study of term-born infants with and�…

Aim To combine meta-analyses of multiple long-term outcomes in children prenatally
exposed to methadone or buprenorphine through their mothers' Opioid maintenance�…

Despite the rising prevalence of methadone treatment in pregnant women with opioid use
disorder, the effects of methadone on neurobehavioral development remain unclear. We�…

Environmental exposures including toxins and nutrition may hamper the developing brain in
utero, limiting the brain's reserve capacity and increasing the risk for Alzheimer's disease�…

Background While the health, social, and economic impacts of opioid addiction on adults
and their communities are well known, the impact of maternal opioid use on the fetus�…

Coincident with the opioid epidemic in the United States has been a dramatic increase in the
number of children born with neonatal abstinence syndrome (NAS), a form of withdrawal�…