Downregulation of microRNA-30 facilitates podocyte injury and is prevented by glucocorticoids

J Wu, C Zheng, Y Fan, C Zeng, Z Chen…�- Journal of the�…, 2014 - journals.lww.com
MicroRNAs (miRNAs) are essential for podocyte homeostasis, and the miR-30 family may
be responsible for this action. However, the exact roles and clinical relevance of miR-30s�…

Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury

Q Wei, K Bhatt, HZ He, QS Mi, VH Haase…�- Journal of the American�…, 2010 - journals.lww.com
MicroRNAs are endogenous, noncoding, small RNAs that regulate expression and function
of genes, but little is known about regulation of microRNA in the kidneys under normal or�…

MicroRNAs as master regulators of glomerular function in health and disease

P Trionfini, A Benigni�- Journal of the American Society of�…, 2017 - journals.lww.com
MicroRNAs (miRNAs) are important regulators of gene expression, and the dysregulation of
miRNAs is a common feature of several diseases. More miRNAs are identified almost daily�…

MicroRNAs as mediators and therapeutic targets in chronic kidney disease

JM Lorenzen, H Haller, T Thum�- Nature Reviews Nephrology, 2011 - nature.com
Chronic kidney disease (CKD) is characterized by tubulointerstitial deposition of
extracellular matrix, tubular atrophy and dilatation; the replacement of organ architecture by�…

Non-coding RNA and diabetic kidney disease

H Ren, Q Wang�- DNA and Cell Biology, 2021 - liebertpub.com
Diabetic kidney disease (DKD) is one of the most common chronic microvascular
complications of diabetes. In addition to the characteristic clinical manifestations of�…

Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function

N Sandbo, N Dulin�- Translational Research, 2011 - Elsevier
Myofibroblasts are modified fibroblasts characterized by the presence of a well-developed
contractile apparatus and the formation of robust actin stress fibers. These mechanically�…

[HTML][HTML] The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway

R Li, ACK Chung, Y Dong, W Yang, X Zhong, HY Lan�- Kidney international, 2013 - Elsevier
The TGF-β/Smad3 pathway plays a major role in tissue fibrosis, but the precise mechanisms
are not fully understood. Here we identified microRNA miR-433 as an important component�…

Redox regulation in cancer stem cells

S Ding, C Li, N Cheng, X Cui, X Xu…�- Oxidative medicine and�…, 2015 - Wiley Online Library
Reactive oxygen species (ROS) and ROS‐dependent (redox regulation) signaling pathways
and transcriptional activities are thought to be critical in stem cell self‐renewal and�…

Long noncoding RNA LINC01619 regulates microRNA-27a/forkhead box protein O1 and endoplasmic reticulum stress-mediated podocyte injury in diabetic�…

X Bai, J Geng, X Li, J Wan, J Liu, Z Zhou…�- Antioxidants & redox�…, 2018 - liebertpub.com
Aims: Altered activities of long noncoding RNAs (lncRNAs) have been implicated in the
regulation of microRNAs. microRNA-27a (miR-27a) upregulation has been shown to induce�…

MicroRNA and ER stress in cancer

T Kim, CM Croce�- Seminars in cancer biology, 2021 - Elsevier
The development of biological technologies in genomics, proteomics, and bioinformatics
has led to the identification and characterization of the complete set of coding genes and�…