Vitamin C is a kinase inhibitor: dehydroascorbic acid inhibits IκBα kinase β

JM C�rcamo, A Pedraza, O B�rquez-Ojeda…�- …�and cellular biology, 2004 - Taylor & Francis
Reactive oxygen species (ROS) are key intermediates in cellular signal transduction
pathways whose function may be counterbalanced by antioxidants. Acting as an antioxidant�…

Promoting a pro-oxidant state in skeletal muscle: Potential dietary, environmental, and exercise interventions for enhancing endurance-training adaptations

AC Jordan, CGR Perry, AJ Cheng�- Free Radical Biology and Medicine, 2021 - Elsevier
Accumulating evidence now shows that supplemental antioxidants including vitamin C,
vitamin E and N-Acetylcysteine consumption can suppress adaptations to endurance-type�…

Multilevel selection in a complex adaptive system: The problem of language origins

TW Deacon�- Evolution and learning: The Baldwin effect�…, 2003 - direct.mit.edu
Theories of language origins have almost universally been embarrassments to empirical
science. This is because they are typically like narratives exemplifying certain linguistic�…

[HTML][HTML] Ascorbic acid and the brain: rationale for the use against cognitive decline

FE Harrison, GL Bowman, MC Polidori�- Nutrients, 2014 - mdpi.com
This review is focused upon the role of ascorbic acid (AA, vitamin C) in the promotion of
healthy brain aging. Particular attention is attributed to the biochemistry and neuronal�…

[HTML][HTML] Molecular Decay of the Tooth Gene Enamelin (ENAM) Mirrors the Loss of Enamel in the Fossil Record of Placental Mammals

RW Meredith, J Gatesy, WJ Murphy, OA Ryder…�- PLoS�…, 2009 - journals.plos.org
Vestigial structures occur at both the anatomical and molecular levels, but studies
documenting the co-occurrence of morphological degeneration in the fossil record and�…

[HTML][HTML] Estimating Vitamin C Intake Requirements in Diabetes Mellitus: Analysis of NHANES 2017–2018 and EPIC-Norfolk Cohorts

AC Carr, H Lunt, NJ Wareham, PK Myint�- Antioxidants, 2023 - mdpi.com
Vitamin C is an essential enzyme cofactor and antioxidant with pleiotropic roles in human
physiology. Circulating vitamin C concentrations are lower in people with diabetes mellitus�…

Caveolin-1–mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype

CC Portugal, R Socodato, T Canedo, CM Silva…�- Science�…, 2017 - science.org
Vitamin C is essential for the development and function of the central nervous system (CNS).
The plasma membrane sodium–vitamin C cotransporter 2 (SVCT2) is the primary mediator�…

Variation of ascorbic acid concentration in fruits of cultivated and wild apples

T Fang, Q Zhen, L Liao, A Owiti, L Zhao, SS Korban…�- Food chemistry, 2017 - Elsevier
Ascorbic acid (AsA) content in mature fruits of 457 apple accessions were measured, and a
great variation in AsA concentration was detected. Wild fruits showed significantly higher�…

[HTML][HTML] Human skeletal muscle ascorbate is highly responsive to changes in vitamin C intake and plasma concentrations

AC Carr, SM Bozonet, JM Pullar, JW Simcock…�- The American journal of�…, 2013 - Elsevier
Background: Vitamin C (ascorbate) is likely to be essential for skeletal muscle structure and
function via its role as an enzyme cofactor for collagen and carnitine biosynthesis. Vitamin C�…

Dysphagia, texture modification, the elderly and micronutrient deficiency: a review

BG Rodd, AA Tas, KDA Taylor�- Critical Reviews in Food Science�…, 2022 - Taylor & Francis
Dysphagia is an underlying symptom of many health issues affecting a person's ability to
swallow. Being unable to swallow correctly may limit food intake and subsequently�…