Ascorbic acid (vitamin C) is an enzyme co-factor in eukaryotes that also plays a critical role
in protecting photosynthetic eukaryotes against damaging reactive oxygen species derived�…

Abstract GDP-Mannose 3′, 5′-epimerase (GME; EC 5.1. 3.18) catalyses the conversion of
GDP-d-mannose to GDP-l-galactose, an important step in the ascorbic acid (AsA)�…

Hypertension is epidemic and currently affects 25% of the world's population and is a major
cause of stroke, congestive heart failure, and end-stage renal disease. Interestingly, there is�…

The evolutionary history of sour taste has been little studied. Through a combination of
literature review and trait mapping on the vertebrate phylogenetic tree, we consider the�…

This article provides a comprehensive review on ascorbate metabolism in animal cells,
especially in hepatocytes. The authors deal with the synthesis and the breakdown of�…

Vitamin C, also known as ascorbic acid, is used as a treatment modality in depigmentation of
hyperpigmented spots on the skin and gingiva. This systematic review discusses the studies�…

Introduction: Neutrophil extracellular trap (NET) formation was recently identified as a novel
mechanism to kill pathogens. However, excessive NET formation in sepsis can injure host�…

Two sodium-dependent vitamin C transporters, hSVCT1 and hSVCT2, were cloned from a
human kidney cDNA library. hSVCT1 had a 1797 bp open reading frame encoding a 598�…

2-O-β-d-Glucopyranosyl-l-ascorbic acid (AA-2βG) is a natural and stable ascorbic acid
derivative isolated from the fruits of Lycium barbarum. In our present study�…

Vitamin C, a water-soluble glucose derivative, has considerable antioxidant activity in vitro,
in part because of its ease of oxidation and because the semidehydroascorbate radical�…