Recent advances have made it possible to analyze high-throughput marker-gene
sequencing data without resorting to the customary construction of molecular operational�…

Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the�…

Background The accuracy of microbial community surveys based on marker-gene and
metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA�…

Abstract The NIH Human Microbiome Project (HMP) has been carried out over ten years and
two phases to provide resources, methods, and discoveries that link interactions between�…

Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from�…

The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources�…

The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in
the frequency of preterm birth among populations within countries, and women of African�…

Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many�…

Obesity is the most common medical condition in women of reproductive age. Obesity during
pregnancy has short term and long term adverse consequences for both mother and child�…

Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of�…