Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in�…

Venoms are integrated phenotypes that evolved independently in, and are used for
predatory and defensive purposes by, a wide phylogenetic range of organisms. The same�…

Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional�…

The application of proteomic tools to the study of snake venoms has led to an impressive
growth in the knowledge about their composition (venomics), immunogenicity�…

The snake is the symbol of medicine due to its association with Asclepius, the Greek God of
medicine, and so with good reasons. More than 725 species of venomous snakes have�…

The venom proteome of the black mamba, Dendroaspis polylepis, from Eastern Africa, was,
for the first time, characterized. Forty-different proteins and one nucleoside were identified or�…

We report on the first application of top-down mass spectrometry in snake venomics. De
novo sequence tags generated by, and ProSight Lite supported analysis of, combined�…

Abstract The Indian krait (Bungarus caeruleus) is one of the “Big Four” venomous snakes
widely distributed in South Asia. The present venomic study reveals that its venom (Sri�…

The venom proteome of Hydrophis schistosus (syn: Enhydrina schistosa) captured in
Malaysian waters was investigated using reverse-phase HPLC, SDS-PAGE and high�…

Antivenoms are fundamental in the therapy for snakebites. In elapid venoms, there are
toxins, eg short-chain α-neurotoxins, which are quite abundant, highly toxic, and�…