With the explosion of neuroimaging, differences between male and female brains have been
exhaustively analyzed. Here we synthesize three decades of human MRI and postmortem�…

Depression is the principal cause of illness and disability in the world. Studies charting the
prevalence of depression among children and adolescents report high percentages of�…

The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies�…

The neuro-anatomical substrates of major depressive disorder (MDD) are still not well
understood, despite many neuroimaging studies over the past few decades. Here we�…

Recent neuroimaging studies suggest that the brain adapts with pain, as well as imparts risk
for developing chronic pain. Within this context, we revisit the concepts for nociception, acute�…

Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has�…

Youth (including both childhood and adolescence) is a period when the brain undergoes
dramatic remodeling and is also a time when neuropsychiatric conditions often emerge�…

Depression is a syndrome of stress-and emotion-dysregulation, involving compromised
structural integrity of frontal-limbic networks. Meta-analytic evidence indicates that volumetric�…

Objective To enhance the quality of care and clinical outcomes for children and adolescents
with major depressive disorder (MDD) and persistent depressive disorder (PDD). The aims�…

What we know about cortical development during adolescence largely stems from analyses
of cross‐sectional or cohort‐sequential samples, with few studies investigating brain�…