[HTML][HTML] Quercetin and vitamin C: an experimental, synergistic therapy for the prevention and treatment of SARS-CoV-2 related disease (COVID-19)

RML Colunga Biancatelli, M Berrill…�- Frontiers in�…, 2020 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) represents an emergent
global threat which is straining worldwide healthcare capacity. As of May 27th, the disease�…

Current status of potential therapeutic candidates for the COVID-19 crisis

J Zhang, B Xie, K Hashimoto�- Brain, behavior, and immunity, 2020 - Elsevier
Abstract As of April 15, 2020, the ongoing coronavirus disease 2019 (COVID-2019)
pandemic has swept through 213 countries and infected more than 1,870,000 individuals�…

[HTML][HTML] Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

SL Weiss, MJ Peters, W Alhazzani, MSD Agus…�- Intensive care�…, 2020 - Springer
Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other�…

Intravenous vitamin C in adults with sepsis in the intensive care unit

F Lamontagne, MH Masse, J Menard…�- …�England Journal of�…, 2022 - Mass Medical Soc
Background Studies that have evaluated the use of intravenous vitamin C in adults with
sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown�…

[HTML][HTML] Pilot trial of high-dose vitamin C in critically ill COVID-19 patients

J Zhang, X Rao, Y Li, Y Zhu, F Liu, G Guo, G Luo…�- Annals of intensive�…, 2021 - Springer
Background Few specific medications have been proven effective for the treatment of
patients with severe coronavirus disease 2019 (COVID-19). Here, we tested whether high�…

[HTML][HTML] Oxidative stress and hyper-inflammation as major drivers of severe COVID-19 and long COVID: implications for the benefit of high-dose intravenous vitamin C

C Vollbracht, K Kraft�- Frontiers in Pharmacology, 2022 - frontiersin.org
Oxidative stress is a pivotal point in the pathophysiology of COVID-19 and presumably also
in Long-COVID. Inflammation and oxidative stress are mutually reinforcing each other, thus�…

[HTML][HTML] The role of micronutrients in support of the immune response against viral infections

F Pecora, F Persico, A Argentiero, C Neglia, S Esposito�- Nutrients, 2020 - mdpi.com
Viral infections are a leading cause of morbidity and mortality worldwide, and the importance
of public health practices including handwashing and vaccinations in reducing their spread�…

[HTML][HTML] A new clinical trial to test high-dose vitamin C in patients with COVID-19

AC Carr�- Critical care, 2020 - Springer
With the 2019 novel coronavirus (2019-nCoV) outbreak now spreading across the world,
people are seeking ways in which to potentially protect themselves from the virus or to�…

Electrochemical detection of uric acid and ascorbic acid using r-GO/NPs based sensors

F Mazzara, B Patella, G Aiello, A O'Riordan, C Torino…�- Electrochimica�…, 2021 - Elsevier
A sensitive and selective electrochemical sensor, based on reduced graphene oxide and
gold nanoparticles obtained by simple co-electrodeposition, was developed for the detection�…

[HTML][HTML] The pharmacokinetics of vitamin C

J Lykkesfeldt, P Tveden-Nyborg�- Nutrients, 2019 - mdpi.com
The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family
of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination�…