Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several�…

People with epilepsy frequently have cognitive impairment. The majority of cognitive
problems is influenced by a variety of interlinked factors, including the early onset of�…

In light of the rising prevalence of Alzheimer's disease (AD), new strategies to prevent, halt,
and reverse this condition are needed urgently. Perturbations of brain network activity are�…

The challenges to individuals with epilepsy extend far beyond the seizures. Co‐morbidities
in epilepsy are very common and are often more problematic to individuals than the seizures�…

Interactions between the hippocampus and the cortex are critical for memory. Interictal
epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but�…

Cognitive and behavioural comorbidities are often seen in children with epilepsy, and are
more common and severe in refractory epilepsy. These comorbidities are associated with�…

Objective: We investigated whether interictal epileptiform discharges (IED) in the human
hippocampus are related to impairment of specific memory processes, and which�…

Abstract Parvalbumin-positive (PV+) γ-aminobutyric acid (GABA) interneurons are critically
involved in producing rapid network oscillations and cortical microcircuit computations, but�…

The potential contributions of the brain histaminergic system in neurodegenerative diseases,
and the possiblity of histamine-targeting treatments is attracting considerable interests. The�…

Many studies have shown that patients with Alzheimer's disease (AD) are at increased risk
for developing seizures and epilepsy. However, reported prevalence and incidence of�…