MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown�…

AFL atrial flutter AH arterial hypertension ANS autonomic nervous system APD action
potential duration ARREST-AF Aggressive Risk Factor Reduction Study for Atrial Fibrillation�…

Background Mortality and morbidity are higher among patients with atrial fibrillation and
heart failure than among those with heart failure alone. Catheter ablation for atrial fibrillation�…

Importance Catheter ablation is effective in restoring sinus rhythm in atrial fibrillation (AF),
but its effects on long-term mortality and stroke risk are uncertain. Objective To determine�…

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other�…

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted, focusing on 2006 through October 2012 and�…

Background Current guidelines recommend pulmonary-vein isolation by means of catheter
ablation as treatment for drug-refractory paroxysmal atrial fibrillation. Radiofrequency�…

Sleep apnea is highly prevalent in patients with cardiovascular disease. These disordered
breathing events are associated with a profile of perturbations that include intermittent�…

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted, focusing on 2006 through October 2012 and�…

Background Catheter ablation is less successful for persistent atrial fibrillation than for
paroxysmal atrial fibrillation. Guidelines suggest that adjuvant substrate modification in�…