Planting the seed: origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

LF Stinson, MS Payne, JA Keelan�- Critical reviews in microbiology, 2017 - Taylor & Francis
It has long been assumed that establishment of the fetal microbiome commences with the
birthing process. However, recent studies have found bacterial DNA in umbilical cord blood�…

[HTML][HTML] Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

C Hoskinson, DLY Dai, KL Del Bel, AB Becker…�- Nature�…, 2023 - nature.com
Allergic diseases affect millions of people worldwide. An increase in their prevalence has
been associated with alterations in the gut microbiome, ie, the microorganisms and their�…

Early infancy microbial and metabolic alterations affect risk of childhood asthma

MC Arrieta, LT Stiemsma, PA Dimitriu…�- Science translational�…, 2015 - science.org
Asthma is the most prevalent pediatric chronic disease and affects more than 300 million
people worldwide. Recent evidence in mice has identified a “critical window” early in life�…

[HTML][HTML] Composition and variation of the human milk microbiota are influenced by maternal and early-life factors

S Moossavi, S Sepehri, B Robertson, L Bode, S Goruk…�- Cell host &�…, 2019 - cell.com
Breastmilk contains a complex community of bacteria that may help seed the infant gut
microbiota. The composition and determinants of milk microbiota are poorly understood�…

The maternal serum metabolome by multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform and standardized data workflow�…

M Shanmuganathan, Z Kroezen, B Gill, S Azab…�- Nature�…, 2021 - nature.com
A standardized data workflow is described for large-scale serum metabolomic studies using
multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed�…

[HTML][HTML] Breastmilk feeding practices are associated with the co-occurrence of bacteria in mothers' milk and the infant gut: the CHILD cohort study

K Fehr, S Moossavi, H Sbihi, RCT Boutin, L Bode…�- Cell host &�…, 2020 - cell.com
Gut microbiota play a critical role in infant health. It is now accepted that breastmilk contains
live bacteria from endogenous and exogenous sources, but it remains unclear whether�…

[HTML][HTML] Screen-time is associated with inattention problems in preschoolers: Results from the CHILD birth cohort study

SK Tamana, V Ezeugwu, J Chikuma, DL Lefebvre…�- PloS one, 2019 - journals.plos.org
Background Pre-school children spend an average of two-hours daily using screens. We
examined associations between screen-time on pre-school behavior using data from the�…

Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies

DM Patrick, H Sbihi, DLY Dai, A Al Mamun…�- The Lancet�…, 2020 - thelancet.com
Background Childhood asthma incidence is decreasing in some parts of Europe and North
America. Antibiotic use in infancy has been associated with increased asthma risk. In the�…

[HTML][HTML] 'Human Milk Oligosaccharide Concentrations Are Associated with Multiple Fixed and Modifiable Maternal Characteristics, Environmental Factors, and�…

MB Azad, B Robertson, F Atakora, AB Becker…�- The Journal of�…, 2018 - Elsevier
Abstract Background Human milk oligosaccharides (HMOs) shape the developing gut
microbiome and influence immune function. Aside from genetic Secretor status, the factors�…

Roles of birth mode and infant gut microbiota in intergenerational transmission of overweight and obesity from mother to offspring

HM Tun, SL Bridgman, R Chari, CJ Field…�- JAMA�…, 2018 - jamanetwork.com
Importance Maternal overweight, which often results in cesarean delivery, is a strong risk
factor for child overweight. Little is known about the joint contribution of birth mode and�…