Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this�…

I propose that synchronization affects communication between neuronal groups. Gamma-
band (30–90 Hz) synchronization modulates excitation rapidly enough that it escapes the�…

Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical�…

Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics�…

Alzheimer's disease (AD) is the most common cause of dementia worldwide, but the
molecular and cellular mechanisms underlying cognitive impairment remain poorly�…

Abstract Changes in gamma oscillations (20–50 Hz) have been observed in several
neurological disorders. However, the relationship between gamma oscillations and cellular�…

Over the past 10 years, the development and convergence of microbial opsin engineering,
modular genetic methods for cell-type targeting and optical strategies for guiding light�…

Gamma rhythms are commonly observed in many brain regions during both waking and
sleep states, yet their functions and mechanisms remain a matter of debate. Here we review�…

In order to understand the working brain as a network, it is essential to identify the
mechanisms by which information is gated between regions. We here propose that�…

The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence�…