Background—Pulmonary vein (PV) isolation is a promising new treatment for atrial
fibrillation (AF). We hypothesized that isolation of large areas around both ipsilateral PVs�…

Background—The modification of atrial fibrillation cycle length (AFCL) during catheter
ablation in humans has not been evaluated. Methods and Results—Seventy patients�…

Objectives: We aimed to determine the safety and efficacy of pulmonary vein isolation (PVI)
in atrial fibrillation (AF) patients with impaired left ventricular (LV) systolic function�…

Background—Although segmental or circumferential ablation is effective in eliminating
pulmonary vein (PV)–mediated atrial fibrillation (AF), this procedure may be complicated by�…

Objectives: We conducted this study to compare the efficacy and safety of different catheter
ablation technologies and of distal versus ostial pulmonary veins (PV) isolation using the�…

Various clinical disorders can cause hyperthyroidism, the effects of which vary according to
the patient's age, severity of clinical presentation and association with other comorbidities�…

Adenosine is a nucleoside that impacts the cardiovascular system via the activation of its
membrane receptors, named A1R, A2AR, A2BR and A3R. Adenosine is released during�…

Background—Pulmonary vein isolation (PVI) is increasingly used for treatment of atrial
fibrillation (AF), but few reports exist regarding long-term success. We determined 5-year�…

Background Pulmonary veins (PVs) are important sources of paroxysmal atrial fibrillation.
Long-term rapid atrial pacing (RAP) changes atrial electrophysiology and facilitates the�…

AF is a heterogeneous rhythm disorder that is related to a wide spectrum of etiologies and
has broad clinical presentations. Mechanisms underlying AF are complex and remain�…