Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

KM Kennedy, MC de Goffau, ME Perez-Mu�oz…�- Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a�…

Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease

K Donald, BB Finlay�- Nature Reviews Immunology, 2023 - nature.com
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the�…

[HTML][HTML] Role of human milk bioactives on infants' gut and immune health

LE Carr, MD Virmani, F Rosa, D Munblit…�- Frontiers in�…, 2021 - frontiersin.org
Exclusive human milk feeding of the newborn is recommended during the first 6 months of
life to promote optimal health outcomes during early life and beyond. Human milk contains a�…

Intestinal dysbiosis and rheumatoid arthritis: a link between gut microbiota and the pathogenesis of rheumatoid arthritis

G Horta-Baas, MS Romero-Figueroa…�- Journal of�…, 2017 - Wiley Online Library
Characterization and understanding of gut microbiota has recently increased representing a
wide research field, especially in autoimmune diseases. Gut microbiota is the major source�…

Understanding respiratory microbiome–immune system interactions in health and disease

SK Di Simone, I Rudloff, CA Nold-Petry…�- Science translational�…, 2023 - science.org
Interactions between the developing microbiome and maturing immune system in early life
are critical for establishment of a homeostasis beneficial to both host and commensals. The�…

Microbial transmission, colonisation and succession: from pregnancy to infancy

L Xiao, F Zhao�- Gut, 2023 - gut.bmj.com
The microbiome has been proven to be associated with many diseases and has been used
as a biomarker and target in disease prevention and intervention. Currently, the vital role of�…

[HTML][HTML] Influence of maternal milk on the neonatal intestinal microbiome

KP Gopalakrishna, TW Hand�- Nutrients, 2020 - mdpi.com
The intestinal microbiome plays an important role in maintaining health throughout life. The
microbiota develops progressively after birth and is influenced by many factors, including the�…

An exposome perspective: Early-life events and immune development in a changing world

H Renz, PG Holt, M Inouye, AC Logan…�- Journal of Allergy and�…, 2017 - Elsevier
Advances in metagenomics, proteomics, metabolomics, and systems biology are providing a
new emphasis in research; interdisciplinary work suggests that personalized medicine is on�…

[HTML][HTML] Secretory IgA: linking microbes, maternal health, and infant health through human milk

K Donald, C Petersen, SE Turvey, BB Finlay…�- Cell host & microbe, 2022 - cell.com
Secretory immunoglobulin A (SIgA) in human milk plays a central role in complex maternal-
infant interactions that influence long-term health outcomes. Governed by genetics and�…

[HTML][HTML] Diversity of human milk oligosaccharides and effects on early life immune development

V Ayechu-Muruzabal, AH Van Stigt, M Mank…�- Frontiers in�…, 2018 - frontiersin.org
One of the well-known features of human milk, is the capacity to protect against the risk and
impact of neonatal infections, as well as to influence the onset of allergic and metabolic�…