Antimicrobial resistance monitoring of water environments: a framework for standardized methods and quality control
Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in
the water environment that contribute to its evolution and spread. Environmental monitoring�…
the water environment that contribute to its evolution and spread. Environmental monitoring�…
Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most�…
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most�…
Detection of mobile genetic elements associated with antibiotic resistance in Salmonella enterica using a newly developed web tool: MobileElementFinder
MHK Johansson, V Bortolaia…�- Journal of�…, 2021 - academic.oup.com
Objectives Antimicrobial resistance (AMR) in clinically relevant bacteria is a growing threat
to public health globally. In these bacteria, antimicrobial resistance genes are often�…
to public health globally. In these bacteria, antimicrobial resistance genes are often�…
[HTML][HTML] Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
Large serine recombinases (LSRs) are DNA integrases that facilitate the site-specific
integration of mobile genetic elements into bacterial genomes. Only a few LSRs, such as�…
integration of mobile genetic elements into bacterial genomes. Only a few LSRs, such as�…
Deciphering the mobility and bacterial hosts of antibiotic resistance genes under antibiotic selection pressure by metagenomic assembly and binning approaches
The presence of antibiotics can exert significant selection pressure on the emergence and
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB)�…
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB)�…
mobileOG-db: a manually curated database of protein families mediating the life cycle of bacterial mobile genetic elements
Bacterial mobile genetic elements (MGEs) encode functional modules that perform both core
and accessory functions for the element, the latter of which are often only transiently�…
and accessory functions for the element, the latter of which are often only transiently�…
[HTML][HTML] Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene�…
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene�…
Globally distributed mining-impacted environments are underexplored hotspots of multidrug resistance genes
Mining is among the human activities with widest environmental impacts, and mining-
impacted environments are characterized by high levels of metals that can co-select for�…
impacted environments are characterized by high levels of metals that can co-select for�…
The role of integrative and conjugative elements in antibiotic resistance evolution
J Botelho, H Schulenburg�- Trends in microbiology, 2021 - cell.com
Mobile genetic elements (MGEs), such as plasmids and integrative and conjugative
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution�…
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution�…
VRprofile2: detection of antibiotic resistance-associated mobilome in bacterial pathogens
M Wang, YX Goh, C Tai, H Wang, Z Deng…�- Nucleic acids�…, 2022 - academic.oup.com
VRprofile2 is an updated pipeline that rapidly identifies diverse mobile genetic elements in
bacterial genome sequences. Compared with the previous version, three major�…
bacterial genome sequences. Compared with the previous version, three major�…