Background: The environment surrounding Helicobacter pylori eradication treatment is
dramatically changing. Recently, vonoprazan, a first-in-class potassium-competitive acid�…

Helicobacter pylori (Hp) infection and overexpression of hepatoma-derived growth factor
(HDGF) are involved in gastric carcinogenesis. However, the relationship between Hp�…

The overall prognosis of gastric cancer has gradually improved over the past decades with
growing awareness of potential carcinogens, surveillance programs and early diagnosis, as�…

A study conducted by the Japan Gast Study Group showed that eradication of Helicobacter
pylori reduced the risk of gastric cancer by about one‐third. However, it did not completely�…

With the rising prevalence of antimicrobial resistance, the failure rate of the standard triple
therapy for Helicobacter pylori infection is increasing. Sequential therapy and concomitant�…

In Japan, efforts have been directed toward improving the detection of early gastric cancer
by double contrast radiography and endoscopy, since early cancer has a good prognosis�…

Due to the increasing prevalence of clarithromycin resistance, future of management of
Helicobacter pylori (H. pylori) infections need to be recognized. To now, clarithromycin was�…

Background Helicobacter pylori infection is a risk factor for gastric cancer, and it has been
reported that eradication of H. pylori is effective for preventing such cancer. Recently, H�…

Introduction Helicobacter pylori (H. pylori) has occupied a significant place among infectious
pathogens and it has been documented as a leading challenge due to its higher resistance�…

Background: Whether Helicobacter pylori eradication could reduce the risk of metachronous
gastric cancer remain controversial. In the present study, we performed a systematic review�…