The anterior insular cortex (AIC) is implicated in a wide range of conditions and behaviours,
from bowel distension and orgasm, to cigarette craving and maternal love, to decision�…

Researchers have wondered how the brain creates emotions since the early days of
psychological science. With a surge of studies in affective neuroscience in recent decades�…

The inadequacy of a categorial approach to mental health diagnosis is now well-recognised,
with many authors, diagnostic manuals and funding bodies advocating a dimensional, trans�…

This article addresses the neuroanatomical evidence for a progression of integrative
representations of affective feelings from the body that lead to an ultimate representation of�…

In the last fifteen years, functional neuroimaging techniques have been used to investigate
the neuroanatomical correlates of sexual arousal in healthy human subjects. In most studies�…

The von Economo neurons (VENs) are large bipolar neurons located in the frontoinsular
cortex (FI) and limbic anterior (LA) area in great apes and humans but not in other primates�…

Functional Magnetic Resonance Imaging (fMRI) demonstrates that the subliminal
presentation of arousing stimuli can activate subcortical brain regions independently of�…

Major depressive disorder (MDD) is characterized by a dysregulated fronto-limbic network.
The hyperactivation of limbic regions leads to increased attention and processing of�…

The human insular cortex is involved in a wide range of functions including motor control,
language, and homeostatic regulation. Little is known, however, how these functions are�…

Introduction Brain imaging is becoming a powerful tool in the study of human cerebral
functions related to close personal relationships. Outside of subcortical structures�…