Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle
Ischemic neuronal death causes serious lifelong neurological deficits; however, there is no
proven effective treatment that can prevent neuronal death after the ischemia. We�…
proven effective treatment that can prevent neuronal death after the ischemia. We�…
[HTML][HTML] Brain-derived neurotrophic factor in pediatric acquired brain injury and recovery
A Treble-Barna, BA Petersen, Z Stec, YP Conley…�- Biomolecules, 2024 - mdpi.com
We review emerging preclinical and clinical evidence regarding brain-derived neurotrophic
factor (BDNF) protein, genotype, and DNA methylation (DNAm) as biomarkers of outcomes�…
factor (BDNF) protein, genotype, and DNA methylation (DNAm) as biomarkers of outcomes�…
[HTML][HTML] Targeting the Erk1/2 and autophagy signaling easily improved the neurobalst differentiation and cognitive function after young transient forebrain ischemia�…
F Wang, Z Xia, P Sheng, Y Ren, J Liu, L Ding…�- Cell Death�…, 2022 - nature.com
The hippocampal neurogenesis occurs constitutively throughout adulthood in mammalian
species, but declines with age. In this study, we overtly found that the neuroblast proliferation�…
species, but declines with age. In this study, we overtly found that the neuroblast proliferation�…
[HTML][HTML] Прогностическая значимость и терапевтический потенциал мозгового нейротрофическго фактора BDNF при повреждении головного мозга (обзор)
ИВ Острова, НВ Голубева, АН Кузовлев…�- Общая�…, 2019 - cyberleninka.ru
Нейротрофины—это белки, играющие важную роль в функционировании нервной
системы, регулируя клеточную пролиферацию, дифференцировку, процессы�…
системы, регулируя клеточную пролиферацию, дифференцировку, процессы�…
[HTML][HTML] Prognostic value and therapeutic potential of brain-derived neurotrophic factor (BDNF) in brain injuries
IV Ostrova, NV Golubeva, AN Kuzovlev…�- General�…, 2019 - reanimatology.com
Neurotrophins are proteins that play an important role in the nervous system functioning by
regulating cell proliferation, differentiation, processes of neuronal survival and death, and by�…
regulating cell proliferation, differentiation, processes of neuronal survival and death, and by�…
[HTML][HTML] Enhanced autophagy interacting proteins negatively correlated with the activation of apoptosis-related caspase family proteins after focal ischemic stroke of�…
J Wang, Z Xia, P Sheng, M Shen, L Ding, D Liu…�- BMC neuroscience, 2022 - Springer
Background Neuronal injury induced in young rats by cerebral ischemia reperfusion (CIR) is
known to differ substantially from that in adult rats. In the present study, we investigated the�…
known to differ substantially from that in adult rats. In the present study, we investigated the�…
Effects of ischemic preconditioning on VEGF and pFlk-1 immunoreactivities in the gerbil ischemic hippocampus after transient cerebral ischemia
YS Park, JH Cho, IH Kim, GS Cho, JH Cho…�- Journal of the�…, 2014 - Elsevier
Ischemia preconditioning (IPC) displays an important adaptation of the CNS to sub-lethal
ischemia. In the present study, we examined the effect of IPC on immunoreactivities of VEGF�…
ischemia. In the present study, we examined the effect of IPC on immunoreactivities of VEGF�…
[HTML][HTML] Effect of hyperthermia on calbindin-D 28k immunoreactivity in the hippocampal formation following transient global cerebral ischemia in gerbils
JC Lee, JH Cho, TK Lee, IH Kim, MH Won…�- Neural Regeneration�…, 2017 - journals.lww.com
Abstract Calbindin D-28K (CB), a Ca 2+-binding protein, maintains Ca 2+ homeostasis and
protects neurons against various insults. Hyperthermia can exacerbate brain damage�…
protects neurons against various insults. Hyperthermia can exacerbate brain damage�…
[HTML][HTML] Постреанимационные изменения экспрессии глиального нейротрофического фактора (GDNF): взаимосвязь с повреждением клеток Пуркинье�…
МШ Аврущенко, ИВ Острова…�- Общая�…, 2014 - cyberleninka.ru
Цель исследования: установить значение уровня экспрессии белка GDNF в развитии
процесса гибели клеток Пуркинье мозжечка после ишемии-реперфузии. Материалы и�…
процесса гибели клеток Пуркинье мозжечка после ишемии-реперфузии. Материалы и�…
[HTML][HTML] Difference in transient ischemia-induced neuronal damage and glucose transporter-1 immunoreactivity in the hippocampus between adult and young gerbils
SM Park, JC Lee, BH Chen, BN Shin…�- Iranian Journal of�…, 2016 - ncbi.nlm.nih.gov
Objective (s): The alteration of glucose transporters is closely related with the pathogenesis
of brain edema. We compared neuronal damage/death in the hippocampus between adult�…
of brain edema. We compared neuronal damage/death in the hippocampus between adult�…