During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be�…

Many cellular functions are regulated by calcium (Ca2+) signals that are generated by
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium�…

People with epilepsy frequently have cognitive impairment. The majority of cognitive
problems is influenced by a variety of interlinked factors, including the early onset of�…

Hippocampal neurogenesis continues throughout life and has been suggested to play an
essential role in maintaining spatial cognitive function under physiological conditions. An�…

Recording electrophysiological information such as brain neural signals is of great
importance in health monitoring and disease diagnosis. However, foreign body response�…

Experimental models of epilepsy are useful to identify potential mechanisms of
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA)�…

With advances in healthcare and an ageing population, the number of older adults with
epilepsy is set to rise substantially across the world. In developed countries the highest�…

Alzheimer's disease (AD) is the most common form of dementia present in older adults; its
etiology involves genetic and environmental factors. In recent years, epidemiological studies�…

As the most abundant cell types in the brain, astrocytes form a tissue-wide signaling network
that is responsible for maintaining brain homeostasis and regulating various brain activities�…

People with Alzheimer's disease (AD) have significantly higher rates of subclinical and overt
epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal�…