Research over the past two decades broadly supports the claim that mindfulness meditation—
practiced widely for the reduction of stress and promotion of health—exerts beneficial effects�…

The amygdala has long been associated with emotion and motivation, playing an essential
part in processing both fearful and rewarding environmental stimuli. How can a single�…

Biomarkers have transformed modern medicine but remain largely elusive in psychiatry,
partly because there is a weak correspondence between diagnostic labels and their�…

Uncertainty about a possible future threat disrupts our ability to avoid it or to mitigate its
negative impact and thus results in anxiety. Here, we focus the broad literature on the�…

Negative emotional stimuli activate a broad network of brain regions, including the medial
prefrontal (mPFC) and anterior cingulate (ACC) cortices. An early influential view�…

This paper reviews and synthesizes functional imaging research that over the past decade
has begun to offer new insights into the brain mechanisms underlying emotion regulation�…

The capacity to control emotion is important for human adaptation. Questions about the
neural bases of emotion regulation have recently taken on new importance, as functional�…

The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this�…

Contexts surround and imbue meaning to events; they are essential for recollecting the past,
interpreting the present and anticipating the future. Indeed, the brain's capacity to�…

Mindfulness—as a state, trait, process, type of meditation, and intervention has proven to be
beneficial across a diverse group of psychological disorders as well as for general stress�…