Recent advances have made it possible to analyze high-throughput marker-gene
sequencing data without resorting to the customary construction of molecular operational�…

Microbiome research has grown rapidly over the past decade, with a proliferation of new
methods that seek to make sense of large, complex data sets. Here, we survey two of the�…

Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and�…

From tropical forests to gut microbiomes, ecological communities host notably high numbers
of coexisting species. Beyond high biodiversity, communities exhibit a range of complex�…

Microglial function declines during aging. The interaction of microglia with the gut microbiota
has been well characterized during development and adulthood but not in aging. Here, we�…

Differential abundance analysis is controversial throughout microbiome research. Gold
standard approaches require laborious measurements of total microbial load, or absolute�…

Organisms—especially microbes—tend to live together in ecosystems. While some of these
ecosystems are very biodiverse, others are not, and while some are very stable over time�…

Background Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases
including Crohn's Disease (CD) and ulcerative colitis (UC), which causes inflammation of�…

Inflammatory bowel diseases (IBD) can be broadly divided into Crohn's disease (CD) and
ulcerative colitis (UC) from their clinical phenotypes. Over 150 host susceptibility genes have�…

Microplastics (MPs) are a widely recognized global problem due to their prevalence in
natural environments and the food chain. However, the impact of microplastics on human�…