Gestational Diabetes Mellitus (GDM) is a transitory metabolic condition caused by
dysregulation triggered by intolerance to carbohydrates, dysfunction of beta-pancreatic and�…

Gestational diabetes is characterised by glucose intolerance with onset or first recognition
during pregnancy. The disease shows facets of the metabolic syndrome including obesity�…

Obese pregnant women have increased levels of proinflammatory cytokines in maternal
circulation and placental tissues. However, the pathways contributing to placental�…

Objective Studies in adipose tissue and skeletal muscle suggest that impaired insulin action
is due to defects in the insulin signaling pathway and may play a role in the pathophysiology�…

The fetus requires amino acids for the processes of protein synthesis, carbon accretion,
oxidative metabolism, and biosynthesis, which ultimately determine growth rate in utero. The�…

Introduction Placental fatty acid (FA) uptake and metabolism depend on maternal supply
which may be altered when women have a high pre-pregnancy body mass index (BMI) or�…

Background Insulin resistance (IR) during gestational diabetes mellitus (GDM) has been
linked to dysregulated insulin-PI3K/Akt pathway. A defective insulin-PI3K/Akt pathway and�…

One of the most common complications during pregnancy is gestational diabetes mellitus
(GDM), hyperglycemia that occurs for the first time during pregnancy. The condition is�…

We have reviewed the scientific literature related to four diseases in which to serotonin (5-
HT) is involved in the etiology, herein named 5-HT-linked diseases, and whose prevalence�…

Background: Gestational diabetes mellitus (GDM) is associated with increased fetal
adiposity, which may increase the risk of obesity in adulthood. The placenta has insulin�…