Evidence-based guidelines and secondary meta-analysis for the use of transcranial direct current stimulation in neurological and psychiatric disorders

F Fregni, MM El-Hagrassy…�- International Journal�…, 2021 - academic.oup.com
Background Transcranial direct current stimulation has shown promising clinical results,
leading to increased demand for an evidence-based review on its clinical effects. Objective�…

Alcohol use disorders

AF Carvalho, M Heilig, A Perez, C Probst, J Rehm�- The Lancet, 2019 - thelancet.com
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use
and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent�…

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen…�- Nature�…, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many
complex diseases and disorders. They are heritable, and etiologically related, behaviors that�…

[HTML][HTML] Brain lesions disrupting addiction map to a common human brain circuit

J Joutsa, K Moussawi, SH Siddiqi, A Abdolahi…�- Nature medicine, 2022 - nature.com
Drug addiction is a public health crisis for which new treatments are urgently needed. In rare
cases, regional brain damage can lead to addiction remission. These cases may be used to�…

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann�- Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for�…

Hot and cold executive functions in the brain: A prefrontal-cingular network

MA Salehinejad, E Ghanavati…�- Brain and�…, 2021 - journals.sagepub.com
Executive functions, or cognitive control, are higher-order cognitive functions needed for
adaptive goal-directed behaviours and are significantly impaired in majority of�…

Prevention and treatment of opioid misuse and addiction: a review

ND Volkow, EB Jones, EB Einstein, EM Wargo�- JAMA psychiatry, 2019 - jamanetwork.com
Importance More than 42 000 Americans died of opioid overdoses in 2016, and the fatalities
continue to increase. This review analyzes the factors that triggered the opioid crisis and its�…

The transition to compulsion in addiction

C L�scher, TW Robbins, BJ Everitt�- Nature Reviews Neuroscience, 2020 - nature.com
Compulsion is a cardinal symptom of drug addiction (severe substance use disorder).
However, compulsion is observed in only a small proportion of individuals who repeatedly�…

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

RK Walters, R Polimanti, EC Johnson…�- Nature�…, 2018 - nature.com
Liability to alcohol dependence (AD) is heritable, but little is known about its complex
polygenic architecture or its genetic relationship with other disorders. To discover loci�…

Circuits and functions of the lateral habenula in health and in disease

H Hu, Y Cui, Y Yang�- Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated�…