The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide, especially as a
result of our aging society, high caloric intake and sedentary lifestyle. Besides the well�…

Substantial evidence shows that skeletal fragility should be considered among the
complications associated with type 2 diabetes. Individuals with type 2 diabetes have�…

It is well established that osteoporosis and diabetes are prevalent diseases with significant
associated morbidity and mortality. Patients with diabetes mellitus have an increased risk of�…

Recent evidence demonstrating an increased fracture risk among obese individuals
suggests that adipose tissue may negatively impact bone health, challenging the traditional�…

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease known by the presence of
elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a�…

Glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1)
are the two primary incretin hormones secreted from the intestine on ingestion of various�…

Obesity is one of the most serious worldwide epidemics of the twenty-first century according
to the World Health Organization. Frequently associated with a number of comorbidities�…

Patients with type 2 diabetes mellitus (T2DM) have an increased risk of fragility fractures
despite increased body weight and normal or higher bone mineral density. The mechanisms�…

Bone homeostasis displays a circadian rhythm with increased resorption during the night
time as compared to day time, a difference that seems—at least partly—to be caused by food�…

It has been increasingly acknowledged that bariatric surgery adversely affects skeletal
health. After bariatric surgery, the extent of high-turnover bone loss is much greater than�…