Cytochrome P450 enzymes that metabolize estrogens are expressed in the mammary
gland, uterus, brain and other target tissues for estrogen action, and this results in the�…

Aromatase cytochrome P450 (P450AROM) enzyme activity catalyzes the conversion of
androgens to estrogens in specific brains areas. During central nervous system�…

The need to seek improved combined oral contraceptive (COC) efficacy, with fewer health
risks and better acceptability, has been ongoing since the introduction of COCs more than�…

There is still extensive disparity in our understanding of how estrogens exert their actions,
particularly in non‐reproductive tissues such as the skin. Although it has been recognized�…

Stromal cells and adipocytes were separated after collagenase treatment of adipose tissue
obtained from women undergoing elective surgery, and these cells were used to study�…

Because estrogen contributes to the promotion and progression of breast cancer, a greater
understanding of the role of estrogen in breast cancer has led to therapeutic strategies�…

Individuals with complete androgen insensitivity syndrome show a female genital phenotype
despite 46, XY gonosomes and the presence of androgen producing testes. This clinical�…

Androgen receptor signaling pathway is necessary to complete spermatogenesis in testes.
Difference between androgen binding location in Sertoli cell classifies androgen receptor�…

Peripheral aromatization of androgens exert estrogenic actions in many tissues. Recently in
situ production of estrogens by aromatase was detected in human bone and cultured�…

Intratumoral Aromatase in Human Breast, Endometrial, and Ovarian Malignancies* | Endocrine
Reviews | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals�…