This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished�…

This paper describes a path integral formulation of the free energy principle. The ensuing
account expresses the paths or trajectories that a particle takes as it evolves over time. The�…

The free energy principle, an influential framework in computational neuroscience and
theoretical neurobiology, starts from the assumption that living systems ensure adaptive�…

This paper develops a Bayesian mechanics for adaptive systems. Firstly, we model the
interface between a system and its environment with a Markov blanket. This affords�…

The aim of this paper is twofold:(1) to assess whether the construct of neural representations
plays an explanatory role under the variational free-energy principle and its corollary�…

Much has been written about the free energy principle (FEP), and much misunderstood. The
principle has traditionally been put forth as a theory of brain function or biological self�…

Living systems break detailed balance at small scales, consuming energy and producing
entropy in the environment to perform molecular and cellular functions. However, it remains�…

The free energy principle (FEP) has been presented as a unified brain theory, as a general
principle for the self-organization of biological systems, and most recently as a principle for a�…

We present a didactic introduction to spectral dynamic causal modeling (DCM), a Bayesian
state-space modeling approach used to infer effective connectivity from noninvasive�…

In theoretical biology, we are often interested in random dynamical systems—like the brain—
that appear to model their environments. This can be formalized by appealing to the�…